Oxon Hill High School was founded in 1925.  It began as a union of five elementary schools and was then called The Oxon Hill Consolidated School.  The second year of its existence, the building was expanded and the high school was enlarged from two to three teachers.  From 1928 to 1938, three additions were added to the building.

The “clipper” mascot was determined from a contest held.  The clipper ship was chosen because it represented speed, slick lines, beauty and sturdiness.  The school's motto,
Navis Semper Naviget ("May the Ship Sail Forever"), was chosen and the yearbook and newspaper were respectively designated the Clipper’s Log and the Searchlight.

In 1948, The Oxon Hill Consolidated School was terminated and the high school was expanded to six grades and moved to a new two-story brick building, equipped with science labs, a cafeteria, a gymnasium and a seated auditorium. 

Oxon Hill was the first school in the county to establish the Top Ten Scholastic Honor Society, honoring the top ten percent of the senior class.  Due to overcrowding, the school operated on a split session until the completion of John Hanson Junior High School.  This is when Oxon Hill High School became a “senior” High School.

In the spring of 1970, renovation of Oxon Hill High School was proposed. In 1977 plans were amended to include an addition of a science and technology center to provide selected students with in-depth educational experiences in technology and scientific fields.  The science and technology center opened in 1982.  It accommodated 500 students that qualified by examination in addition to 1,800 comprehensive students from the communities.  Existing facilities would not accommodate the student population so John Hanson was annexed  as part of the campus and housed the ninth grade. 

In the late 1980’s, building size was increased with two wings of classrooms attached to the main structure, an additional gym, an enlarged media center, improved science labs and additional space for administration and guidance.

In 2003, a new gym was built.  Still, there was a strain on facilities that warranted many temporary classrooms that are still in use today.  In 2005, Oxon Hill High School was granted a brand new building to be built in three to four years.